Health care providers across Dauphin, Cumberland, York, and Lancaster counties are on heightened alert following a state health advisory warning of a rising number of cyclosporiasis infections across Central Pennsylvania.
The Pennsylvania Department of Health (DOH), headquartered in Harrisburg, confirmed that at least 45 domestically acquired cases of the severe gastrointestinal parasite have been confirmed statewide since May 1, with additional suspected cases currently undergoing laboratory testing.
The surge comes as the Centers for Disease Control and Prevention (CDC) added Pennsylvania to a 9-state outbreak cluster linked to contaminated shredded iceberg lettuce supplied by Taylor Farms de Mexico. The recalled produce was distributed to major fast-food locations, including regional Taco Bell restaurants, as well as retail grocers across the Mid-Atlantic.
Because Cyclospora cayetanensis is a hardy microscopic parasite that is not detected through routine hospital bacterial stool cultures, the Department of Health issued a Health Advisory Network (HAN) notice directing medical providers across Mid-State health systems—including UPMC, Penn State Health, and WellSpan—to request specific parasite testing for patients presenting with persistent stomach illness.
National Exposure: The CDC has reported over 4,170 confirmed domestic cases nationwide since May 1, with nearly 2,000 cases specifically tied to fast-food lettuce exposures in Pennsylvania and neighboring states.
Delayed Onset: Symptoms typically take 2 to 14 days to appear after eating contaminated food, meaning local health departments expect case counts to rise as testing catches up with mid-to-late July exposures.
Fast-Food Impact: Major chains across Central Pennsylvania have adjusted supply sources or temporarily removed shredded lettuce from menus out of an abundance of caution while federal regulators trace distribution channels.
Cyclosporiasis is caused by consuming food or water contaminated with microscopic fecal matter. It is not easily spread directly from person to person, but it causes significant gastrointestinal distress.
Key Symptoms to Watch For:
Frequent, watery diarrhea lasting several days or weeks
Severe stomach cramps, bloating, and gas
Loss of appetite and unexpected weight loss
Low-grade fever, nausea, and intense fatigue
Standard washing of produce does not always eliminate the parasite, though cooking vegetables to at least 158°F destroys the organism. Without targeted antibiotic treatment (typically trimethoprim-sulfamethoxazole), symptoms can recur in waves for over a month.
Residents are advised to check their refrigerators and dispose of any recalled Marketside or Taylor Farms iceberg lettuce products and to consult a doctor if gastrointestinal symptoms persist.



